Corticosteroids in Myositis and Scleroderma
نویسندگان
چکیده
منابع مشابه
Evaluation of cancer-associated myositis and scleroderma autoantibodies in breast cancer patients without rheumatic disease.
OBJECTIVES Systemic sclerosis (scleroderma) and dermatomyositis are two prototypic autoimmune diseases that are strongly associated with malignancy. While specific autoantibodies in these diseases are markers of an increased risk of cancer at scleroderma and dermatomyositis onset, it is not known whether these autoantibodies are biomarkers of cancer risk in patients without rheumatic disease. ...
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The anti-PM/Scl autoantibodies are known to characterize a subset of autoimmune patients with myositis, scleroderma (Scl), and the PM/Scl overlap syndrome. The major autoantigens that are recognized by anti-PM/Scl autoantibodies are designated PM/Scl-100 and PM/Scl-75. These autoantigens have been reported to associate into a large complex consisting of 11 to 16 proteins and to play a role in r...
متن کاملCorticosteroids in Infectious Diseases
Accumulated data based on experiences with curtico,teroids in the management uf infectious diseases, have proved that they are very dfective and ,afe drugs provided that are administered properly. The Corticosteroids arc administered mainly bec,1usc o; antitoxic, antiimflammatory a11d antiallcrgic effects, the cndotoxius are ncuturalized, generalized body reactions are diminished, damaged t...
متن کاملEvaluation of methotrexate and corticosteroids for the treatment of localized scleroderma (morphoea) in children.
BACKGROUND Localized scleroderma (LS) or morphoea is often considered to be a benign self-limiting condition confined to the skin and subcutaneous tissue. However, the course of the disease is unpredictable and severe functional and cosmetic disability may result. Drug treatment with systemic corticosteroids in combination with methotrexate has been reported to be beneficial in LS, but data in ...
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ژورنال
عنوان ژورنال: Rheumatic Disease Clinics of North America
سال: 2016
ISSN: 0889-857X
DOI: 10.1016/j.rdc.2015.08.011